I am writing to commend the authors on their insightful and comprehensive study titled "An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk" recently published in Gastroenterology.1 The development of the colorectal cancer (CRC) microbial dietary score (CMDS) is a significant advancement in understanding the diet-microbiome-CRC axis. Notably, the authors used reduced rank regression to create a dietary pattern specifically associated with CRC-related gut microbial features.
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