We read with great interest the MOCCAS study by Carvalho et al1 that explores stool-based testing as a viable alternative to colonoscopy for post-polypectomy colorectal cancer (CRC) surveillance. The study makes a compelling case for reducing the burden of surveillance colonoscopies, yet certain interpretations in the discussion section warrant further scrutiny. Although the investigators acknowledge limitations and perform extensive sensitivity analyses, some key areas need further discussion.
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