The recent article by van Wifferen et al,1 "Combining Colonoscopy with Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study," provides a commendable effort toward optimizing surveillance strategies for familial colorectal cancer (FCRC). Although this study introduces a potentially transformative model, there are aspects within its discussion and interpretation of results that merit further scrutiny and elaboration to fully realize its implications and practical application.
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