The importance of the mesentery in the pathophysiology of Crohn’s disease
The importance of the mesentery in the pathophysiology of Crohn’s disease
Crohns
A Mediterranean Diet for Crohn’s Disease: Embracing Colorful Diversity to Improve the Microbiome
Patients with inflammatory bowel diseases (IBD) frequently ask their providers what to eat. In the absence of clear guidance from their gastrointestinal provider or a knowledgeable dietitian, ...
Epstein-Barr Virus Exposure Precedes Crohn`s Disease Development
Inflammatory bowel diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic, relapsing inflammatory diseases of the gastrointestinal tract that result from a ...
Expand Research in Risk of Developing Crohn’s Disease
The study "Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have a Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a ...
Comments on “Healthy first-degree relatives from multiplex families versus simplex families have a higher subclinical intestinal inflammation, a distinct fecal microbial signature, and harbor a higher risk of developing Crohn’s disease”
We read with great interest the article by Olivera et al1 addressing the elevated risk of Crohn’s disease (CD) in first-degree relatives (FDRs) from multiplex families compared to simplex ...
Capsule Endoscopy–Guided Proactive Treat-to-Target Versus Continued Standard Care in Patients With Quiescent Crohn’s Disease: A Randomized Controlled Trial
Optimizing medical treatment in patients with asymptomatic Crohn’s disease, who are found by capsule endoscopy to still have active intestinal inflammation, can significantly reduce the risk of ...
Efficacy and Safety of Guselkumab Subcutaneous Induction and Maintenance in Participants With Moderately to Severely Active Crohn’s Disease: Results From the Phase 3 GRAVITI Study
Guselkumab is a new treatment for improving Crohn’s disease with a patient-friendly administration option. Guselkumab injections resulted in meaningful improvements in symptoms and the lining of ...
Clinical Trials for Peri-anal Crohn’s Disease: A Call for a Revised Approach
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal tract. Peri-anal complications of CD, which ...
Impact of Parental Crohn’s Disease on Offspring’s Gut Health and Disease Vulnerability
The study by Lee et al1 offers valuable insights into the links between parental Crohn’s disease (CD) and offspring’s gut health and disease risk. However, some aspects need improvement for more ...
TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental Crohn’s disease
Death receptor 3 (DR3) and its ligand, tumor necrosis factor-like ligand 1A (TL1A), regulates the balance between effector and regulatory T cells in IBD. While IL-9-secreting Th9 cells are linked ...