The MODY-Causing Mutation of the Human Carboxyl Ester Lipase Gene (CEL) Triggers Chronic Pancreatitis but not Diabetes in Mice

Carboxyl ester lipase (CEL) is a digestive enzyme expressed by pancreatic acinar cells. The last exon of the CEL gene contains a variable number tandem repeat (VNTR).1 Single-base deletions within ...